Behavioral Studies
We offer behavioral phenotyping services for preclinical neuroscience studies. We can characterize your compound with a battery of tests or focus on a particular test based on your needs. Studies we provide include -
Morris Water Maze
Visuospatial Memory - Schizophrenia, Alzheimer’s Disease Assesses hippocampal-dependent spatial learning and memory Real time measurement of latency to escape, distance traveled, velocity, and path. Drug studies can employ standard strains, like the Spague-Dawley, or a PhysioGenix model.
Elevated Plus Maze
Depression, Anxiety Disorders, Mania Assesses anxiety as less anxious animals spend more time on the open arms. Standard strains or PhysioGenix models with different baseline levels of anxiety can be used. Drug developers can test efficacy of anxiolytics or side effects in real time.
Forced Swim Test
Depression, Anxiety Disorders, Mania Assesses anxiety as less anxious animals spend more time on the open arms. Standard strains or PhysioGenix models with different baseline levels of anxiety can be used. Drug developers can test efficacy of anxiolytics or side effects in real time.
Open Field
Activity Monitor - Anxiety Disorders, Panic Disorders, Locomotor Activity Assesses locomotor activity and exploratory behaviors. Real time measurement of distance traveled, velocity, and time in center area. Measures drug side effects like hyperactivity and sedation along with anxiety.
T Maze
Working Memory Assesses simple learning, visouspatial memory, and spontaneous alternation. 21-day test includes food deprivation, paw preference, training to 80% criterian, and 2 reversals. Assess drugs using standard strains or PhysioGenix models with natural deficits in cognition.
Rotarod
Motor Coordination Assesses motor coordination and fatigue. Evaluate drugs that enhance coordination and measures side effects. A 1-day study includes training and a dose response drug test.
Hot Plate
Pain Assesses the level of upper CNS pain recognition in rodents via a heated platform. Useful for developing analgesics. Employs standard strains or PhysioGenix strains with varying baseline levels of pain sensitivity.

