Available in mice or rats via multiple routes of administration.

• Efficacy
• PK/PD
• Basic Safety Assessments
• Tolerability studies
• Dose range finding studies
• Observations: clinical signs, mortality, body weight, and food and water intake 
• Clinical Chemistry and urine analysis.
• Post Mortem
  
• Clinical blood chemistry 
• Metabolic assays 
• Organ weights 
• Gross necropsy