Preclinical Services

Summary

We specialize in preclinical research services using various proprietary or standard rat models of human disease. We offer custom protocol development that combines the proper animal model with effective drug dosing and environment. Our services are designed to assist our clients in shortening the time and lowering the costs of preclinical drug research by providing superior animal models and a world-renowned scientific team for customized study development.

Fields of Expertise

We specialize in diabetes, behavioral and cardiovascular research, our world-class scientific team bring years of experience to your study.

Product and Service Offering

• Pharmacokinetic and pharmacodynamic dosing of client drug compounds.
• Surgical procedures including uninephrectomy; implantation of femoral catheter, jugular catheter, telemetry
  devices or osmotic pumps.
• Acute and chronic dosing protocols by oral gavage; subcutaneous, IP, intramuscular and tail vein injections; osmotic pump implantation.
• Gross necropsy that includes detection of drug-induced abnormalities, organ removal and preservation for histological or molecular analysis.
• Histopathology that includes organ preservation, generation of tissue slices, staining and scoring by certified pathologists.
• Statistical analysis of data using SigmaSTAT, PRIZM and Excel.
• Data interpretation by experts in cardiovascular and renal physiology.
• Follow-up consulting.