In Vitro Capabilities

Biomarkers

Biomarkers play a critical role in maximizing your understanding of a test compound. We support your drug development efforts by providing a wide range of tests. Below is a sample of the more common biomarkers.

  • Angiotensinogen 
  • Angiotensin Converting Enzyme (ACE) 
  • Beta-2 Microglobulin
  • C-reactive protein 
  • CD40 and CD40 ligand 
  • Cortisol 
  • Cystatin C 
  • Epidermal Growth Factor 
  • Glucagon 
  • Glucagon-like Peptide-1 
  • Glutathione S-Transferase-alpha (GST-alpha) 
  • Glutathione S-Transferase Yb1 (GST Yb1) 
  • Growth Hormone 
  • Insulin
  • Insulin-like Growth Factor, Type 1 
  • Kidney Injury Molecule-1 (KIM-1) 
  • Leptin 
  • Fibrogen 
  • Interleukins 
  • MIPs (macrophage inflammatory protein) 
  • MMPs (matrix-metalloproteinase) 
  • MCPs (monocyte chemotactic protein) 
  • Osteopontin 
  • Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) 
  • Thrombopoietin 
  • Tissue Factor 
  • Tumor Necrosis Factor-alpha 
  • VCAM 
  • Vascular Endothelial growth Factor (VEGF)
  • von Willebrand Factor 
 Please contact us if you are interested in a biomarker not listed.

MASS SPECTROMETRY

In conjunction with the University of Mississippi Medical Center we offer mass spectrometry analysis for drug metabolism studies, including the identification and structure elucidation of metabolites for many drugs. The Mass Spectrometry Core has experience and instrumentation to provide analytical requirements for many pharmacokinetic studies and measuring the molecular weight of isolated or partially isolated peptides and proteins. Facilities include an ABI 4000 QTRAP, gas liquid chromatography/single quadrupole mass spectrometer and an ABI/PSCIEX365 liquid chromatography/triple quadrupole mass spectrometer.